Koichi Hasegawa

This study identifies QKI as a regulator of mitochondrial integrity in COPD, showing its protective role against emphysema through maintenance of mitochondrial function.

The paper identifies region-specific molecular regulatory programs in human distal airways that maintain epithelial identity and mucus homeostasis, revealing mechanisms for mucociliary defense.

This study shows that p53 mutations in Li-Fraumeni syndrome mice reduce B cell activation during germinal center reactions without affecting the ratio of activated B cells in dark and light zones.

This study identifies airway epithelial host defense defects caused by STAT3 mutations in Hyper IgE Syndrome, contributing to chronic pulmonary infection.