Author

Marina Schrecker

Memorial Sloan Kettering Cancer CenterORCID 0000-0001-8542-6657Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:structural biology· 1

Frequent Co-Authors

Richard K. HiteiD· 2 shared Bernd FakleriD· 1 shared Charanya KumariD· 1 shared Dirk RemusiD· 1 shared Juan C. CastanedaiD· 1 shared Rosa Planells‐CasesiD· 1 shared Sujan Devbhandari· 1 shared Sumanta KariD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCell Biology

Richard K. HiteORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintFeb 28, 2025

Structural basis of ClC-3 inhibition by TMEM9 and PI(3,5)P2

Marina Schrecker, Yeeun Son, Rosa Planells‐Cases…·Richard K. Hite

This study identifies TMEM9 and PI(3,5)P2 as regulators of ClC-3 activity through cryo-EM structures showing TMEM9 blocks Cl- ion flow and PI(3,5)P2 stabilizes their interaction.

2 citations

structural biologyexperimental assay

𝕏 PostBluesky

Molecular BiologyeLifePeer-reviewedJul 22, 2022

Multistep loading of PCNA onto DNA by RFC

Marina Schrecker, Juan C. Castaneda, Sujan Devbhandari…·Richard K. Hite

This study reveals the multistep mechanism of PCNA loading by RFC using cryo-EM, showing open and closed PCNA conformations and a revised model for DNA clamp loading.

42 citations

experimental assay

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