Author

Melissa J. Mann

St. Jude Children's Research HospitalORCID 0000-0001-8543-9714Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Anuradha R. Iyer· 1 shared Ashley R. Flory· 1 shared Chris Melendez-Suchi· 1 shared Christopher J. GuerrieroiD· 1 shared Hannah E. VorndraniD· 1 shared Jeffrey L. BrodskyiD· 1 shared Linda M. HendershotiD· 1 shared Maria Sukhoplyasova· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Anuradha R. Iyer

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1 paper

Recent·Most cited

Cell BiologyMolecular Biology of the CellPeer-reviewedMar 6, 2024

Loss of Grp170 results in catastrophic disruption of endoplasmic reticulum functions

Melissa J. Mann, Chris Melendez-Suchi, Hannah E. Vorndran…·Teresa M. Buck

This study shows that loss of Grp170 causes ER dysfunction, including BiP misregulation and UPR activation, leading to cell death in mouse embryonic fibroblasts.

13 citations

mouseproteomics

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