Author

Debiao Li

Cedars-Sinai Medical CenterORCID 0000-0001-8560-8231Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:benchmark study· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:database / resource· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

B Y ZhangiD· 1 shared Candace L. FloydiD· 1 shared Chushu SheniD· 1 shared Dante Rigo De Righi· 1 shared Dmitriy SheyniD· 1 shared Giselle KanedaiD· 1 shared Haochen NaniD· 1 shared Haoran Li· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioengineering

B Y ZhangORCID

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2 papers

Recent·Most cited

BioengineeringbioRxivPreprintJul 28, 2026

✦ In-depth digest

BioPathfinder: Evidence-guided multi-agent platform enables hypothesis discovery for CAR-T engineering

Shubing Wang, Yan-Ruide Li, Qian Wang…·Debiao Li

A provenance-tracked multi-agent system curated 57 CAR-T patient scRNA-seq studies, generated reviewable hypotheses, and prioritized KLRC1/NKG2A, whose blockade improved CD8+ CAR-T antitumour activity in a Raji xenograft model.

1 citation

humanmouse

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Developmental BiologyJOR SpinePeer-reviewedJul 9, 2026

A Porcine Model of Intervertebral Disc Injury Recapitulates Human Discogenic Pain via Notochordal Cell Loss and Pain-inducing Nucleus Pulposus Cell Emergence

Giselle Kaneda, Jacob T. Wechsler, Melissa Chavez…·Dmitriy Sheyn

This study develops a porcine model of intervertebral disc injury that mimics human discogenic pain through notochordal cell loss and nucleus pulposus cell emergence, validated by MRI, biobehavioral testing, and single-cell transcriptomics.

DOI 10.1002/jsp2.70200

plant (other)bulk RNA-seq

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