Author

Yongchao Dou

Baylor College of MedicineORCID 0000-0001-9315-1155Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:protein structure prediction· 1 Organism:rat· 1

Frequent Co-Authors

Bing ZhangiD· 2 shared Shixia HuangiD· 2 shared Yi LiiD· 2 shared Alexandria Z. BuiD· 1 shared Amy Tsu KuiD· 1 shared Arun SreekumariD· 1 shared Bart O. WilliamsiD· 1 shared Bing ZhangiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

Bing ZhangORCID

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3 papers

Recent·Most cited

Cancer BiologyProceedings of the National Academy of SciencesPeer-reviewedJun 22, 2026

Rat somatic genome editing enables ER+ breast cancer modeling

Wen Bu, Tobie D. Lee, Meenakshi Anurag…·Yi Li

This study enables efficient somatic genome editing in rats to model ER+ breast cancer, showing that rat tumors recapitulate key features of human ER+ breast cancer not observed in mice.

DOI 10.1073/pnas.2529653123

ratexperimental assay

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Cancer BiologybioRxivJan 10, 2024

Loss of ZNRF3/RNF43 Unleashes EGFR in Cancer

Fei Yue, Amy Tsu Ku, Payton D. Stevens…·Yi Li

The paper shows that ZNRF3/RNF43 ubiquitinates and degrades EGFR, and their loss increases EGFR signaling, promoting cancer growth.

3 citations

humanproteomics

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BioinformaticsbioRxivPreprintNov 3, 2022

SEPepQuant enables comprehensive protein isoform characterization in shotgun proteomics

Yongchao Dou, Xinpei Yi, Lindsey K. Olsen, Bing Zhang

SEPepQuant improves protein isoform characterization in shotgun proteomics by addressing limitations in existing methods, identifying isoform-level regulation events, and enabling cross-study comparisons.

2 citations

humanproteomics

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