Author

Oleg Brodsky

Pfizer (United States)ORCID 0000-0002-9710-3983Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Ahu Turkoz· 1 shared Anders MälarstigiD· 1 shared Brad T. Townsley· 1 shared Brian S. EganiD· 1 shared Chames KermiiD· 1 shared Clifford R. Restaino· 1 shared Dörte SchlesingeriD· 1 shared Kristen Jensen-PergakesiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Ahu Turkoz

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

KDM5 demethylases suppress R-loop-mediated viral mimicry and DNA damage in breast cancer cells

Lena Lau, Kurt Henderson, Ahu Turkoz, Sara B. Linker, Dörte Schlesinger, Brad T. Townsley, Brian S. Egan, Shoba Ragunathan, Robert A. Rollins, Xianju Bi, Zhijian J. Chen, Oleg Brodsky, Clifford R. Restaino, Murali Gururajan, Kristen Jensen-Pergakes, , Marie Classon

This study shows that KDM5 demethylases suppress R-loop formation in breast cancer cells, reducing DNA damage and enhancing immune-related gene expression without affecting normal cells.

eLife · Oct 13, 2025Peer-reviewedCancer Biology