Multiomic Profiling Links RDH12-Dependent Retinaldehyde Detoxification to Membrane Remodeling and Ferroptosis
KanagaVijayan Dhanabalan, Miranda R. Weigand, Ramya Visvanathan…·Bryon Drown
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Purdue University West LafayetteORCID 0000-0001-8636-2616Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
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KanagaVijayan Dhanabalan, Miranda R. Weigand, Ramya Visvanathan…·Bryon Drown
Trung Thanh Thach, KanagaVijayan Dhanabalan, Shiwangi Maurya…·Subramanian Ramaswamy
This study reveals a bifunctional mechanism in TMAO demethylase where HCHO is channeled from a catalytic core to a THF-binding site, linking TMAO demethylation with one-carbon transfer.
Trung Thanh Thach, KanagaVijayan Dhanabalan, Prajwal P. Nandekar…·Subramanian Ramaswamy
This study identifies a second drug-binding site in P2X3 receptors and shows camlipixant acts as an allosteric inhibitor, providing insights into its selectivity and mechanism of action.
Parveen Goyal, KanagaVijayan Dhanabalan, Mariafrancesca Scalise…·Subramanian Ramaswamy
The paper reports the structures of SiaQM from Fusobacterium nucleatum with and without Neu5Ac, revealing interactions and transport mechanisms.