Author

Sandra Villegas

Universitat Autònoma de BarcelonaORCID 0000-0001-8644-4304Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Organism:C. elegans· 1

Frequent Co-Authors

Jofre Seira CurtoiD· 2 shared M. Rosario FernándeziD· 2 shared Natalia Sánchez de GrootiD· 2 shared Genis Perez Collell· 1 shared Genís Pérez Collell· 1 shared Manuel RuiziD· 1 shared Marina Romero Ruiz· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 17 mutual co-author links

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2 shared papersBiochemistry

Jofre Seira CurtoORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintSep 1, 2026

Sequential Molecular Interactions Shape Aβ42 Aggregation, Propagation, and Toxicity

Jofre Seira Curto, Genis Perez Collell, Manuel Ruiz…·Natalia Sánchez de Groot

The paper investigates how sequential molecular interactions modulate Aβ42 aggregation properties and toxicity across successive cycles, showing that early interactions with exogenous peptides alter aggregate characteristics and propagation.

DOI 10.64898/2026.08.27.747468

proteomicsexperimental assay

𝕏 PostBluesky

BiochemistrybioRxivPreprintJan 24, 2025

Exogenous Amyloid Sequences: Their Role in Amyloid-Beta Heterotypic Aggregation

Jofre Seira Curto, Marina Romero Ruiz, Genís Pérez Collell…·Natalia Sánchez de Groot

The paper investigates how exogenous amyloid sequences from gut microbiota affect Aβ heterotypic aggregation and introduces the 'Interaction History' concept.

DOI 10.1101/2025.01.24.634659

C. elegansproteomics

𝕏 PostBluesky