Molecular BiologybioRxivPreprint
Pateamine A mediates RNA sequence-selective translation repression by anchoring eIF4A and DDX3 to GNG motifs
Hironori Saito, Yuma Handa, Mingming Chen…·Shintaro Iwasaki
This paper identifies pateamine A as a small-molecule compound that selectively represses mRNA translation by anchoring eIF4A and DDX3 to GNG motifs.
DOI 10.1101/2023.09.21.558742