Kaori Fukuzawa

Structural insights into fosfomycin efflux by a streptococcal ABC transporter

This study identifies and characterizes FoeAB, a type IV ABC transporter in Streptococcus pneumoniae that exports fosfomycin, using functional assays and cryo-EM structures.

Structural insights into inhibition mechanism of the helicase-primase complex from human herpesvirus 1

This paper reports cryo-EM structures of the HHV1 helicase-primase complex bound to DNA and inhibitors, revealing how these drugs block viral DNA replication by locking the helicase in an inactive conformation.

Integrating Segmental Deuteration iCM-SANS with SAXS and MD for Dynamical Analysis of Multi-domain Proteins

The paper develops a protocol combining segmental deuteration and multi-step protein ligation with SAXS and iCM-SANS to improve discrimination of conformational ensembles in multi-domain proteins.

Evolutionary and structural basis of SLAM utilization in morbilliviruses - Its implications for host range and cross-species transmission

This study investigates how morbilliviruses use SLAM receptors across species, finding that most can use multiple SLAMs except human SLAM, and that MV adapts to bat SLAM with a single mutation.

Pateamine A mediates RNA sequence-selective translation repression by anchoring eIF4A and DDX3 to GNG motifs

This paper identifies pateamine A as a small-molecule compound that selectively represses mRNA translation by anchoring eIF4A and DDX3 to GNG motifs.