Christopher Kozlowski

Retinal degeneration in a mouse model of CRB1 disease rescued by the photoreceptor-specific CRB1-B isoform

This study shows that restoring the CRB1-B isoform in photoreceptors rescues retinal degeneration in a mouse model of CRB1 disease by preserving adherens junctions.

Retinal neurons establish mosaic patterning by excluding homotypic somata from their dendritic territory

The paper shows that dendrite-soma exclusion mediated by MEGF10 establishes mosaic spacing in mouse retinal starburst amacrine cells.

Rejection of inappropriate synaptic partners mediated by transcellular FLRT2-UNC5 signaling

The paper shows that FLRT2-UNC5 signaling mediates synaptic partner rejection in retinal neurons by eliminating dendrites that stray from their correct sublayers.

Formation of retinal direction-selective circuitry initiated by starburst amacrine cell homotypic contact

The paper shows that starburst amacrine cells use homotypic contacts to initiate formation of a dendritic scaffold in the retina, which is critical for direction-selective circuitry.