Large-scale death of retinal astrocytes duringnormal development mediated by microglia
Vanessa M. Puñal, Caitlin E. Paisley, Federica S. Brecha, Monica A. Lee, Robin M. Perelli, Jingjing Wang, Emily G. O’Koren, Caroline R. Ackley, Daniel R. Saban, Benjamin E. Reese, Jeremy N. Kay
The paper shows that retinal astrocytes undergo large-scale death during development, mediated by microglia rather than apoptosis, leading to anatomical and functional changes in the retinal network.
PLoS Biology · Oct 18, 2019Peer-reviewedNeuroscience