Author

I. M. Kustanovich

University of Haifa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Rami I. AqeilaniD· 3 shared Shani SterniD· 3 shared Srinivasarao RepudiiD· 2 shared Afifa Saleem· 1 shared Asia ZoncaiD· 1 shared Baraa Abudiab· 1 shared Dania AbdellatifiD· 1 shared Daniel J SteinbergiD· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersNeuroscience

Rami I. AqeilanORCID

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3 papers

Recent·Most cited

WWOX deficiency impairs neurogenesis and neuronal function in human organoids

Daniel J. Steinberg, Asia Zonca, Dania Abdellatif, Idan Rosh, I. M. Kustanovich, Osama Hidmi, Kian Maroun, Shani Stern, José Dávila-Velderrain, Rami I. Aqeilan

This study identifies WWOX mutations' impact on neurogenesis and neuronal function in human organoids, showing gene therapy can restore function.

bioRxiv · Dec 22, 2024 · PreprintNeuroscience

Neonatal neuronal WWOX gene therapy rescues Wwox null phenotypes

Srinivasarao Repudi, I. M. Kustanovich, Sara Abu‐Swai, Shani Stern, Rami I. Aqeilan

This study shows that gene therapy using an AAV vector to restore WWOX expression in neurons rescues multiple neurological defects in Wwox-null mice.

EMBO Molecular Medicine · Nov 7, 2021Peer-reviewedNeuroscience

Modeling Genetic Epileptic Encephalopathies using Brain Organoids

Daniel J Steinberg, Srinivasarao Repudi, Afifa Saleem, I. M. Kustanovich, Sergey V. Viukov, Baraa Abudiab, Ehud Banne, Muhammad Mahmoud Mahajnah, Jacob H. Hanna, Shani Stern, Peter Louis Carlen, Rami I. Aqeilan

This study uses brain organoids to model WOREE, a severe epileptic encephalopathy, identifying CNS abnormalities and showing potential therapeutic rescue via WWOX expression.

EMBO Molecular Medicine · Jul 15, 2021Peer-reviewedNeuroscience