Author

María Tristán‐Manzano

Universidad de GranadaORCID 0000-0001-8721-1414Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:CITE-seq· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Concha HerreraiD· 2 shared Francisco Martı́niD· 2 shared Juan Antonio MarchaliD· 2 shared Kristina PavloviciD· 2 shared Marina Cortijo-GutierréziD· 2 shared Noelia Maldonado‐PéreziD· 2 shared Pedro Justicia-LirioiD· 2 shared Pilar MuñoziD· 2 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersImmunology

Concha HerreraORCID

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2 papers

Recent·Most cited

ImmunologyMolecular Therapy — Nucleic AcidsPeer-reviewedAug 15, 2024

First-in-class Transactivator-Free, Doxycycline-inducible IL-18-engineered CAR-T cells for relapsed/refractory B-cell lymphomas

Pedro Justicia-Lirio, María Tristán‐Manzano, Noelia Maldonado‐Pérez…·Francisco Martín

This paper develops doxycycline-inducible IL-18 CAR-T cells (iTRUCK19.18) that enhance antitumor activity while controlling IL-18 release through dual mechanisms.

7 citations

humanCITE-seq

𝕏 PostBluesky

Genetic & Genomic MedicineMolecular Therapy — OncolyticsPeer-reviewedMay 17, 2022

Physiological (TCR-like) regulated lentiviral vectors for the generation of improved CAR-T cells

María Tristán‐Manzano, Noelia Maldonado‐Pérez, Pedro Justicia-Lirio…·Francisco Martı́n

This paper develops lentiviral vectors with TCR-like expression patterns to generate CAR-T cells with reduced tonic signaling and improved therapeutic profiles.

25 citations

humanexperimental assay

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