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Author

Pedro Justicia-Lirio

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Centro de Investigación Médica AplicadaORCID 0000-0002-6823-7747Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:clustering· 1Research Focus:drug response / drug discovery· 1Approach:experimental assay· 1Organism:human· 1Organism:mouse· 1Assay:scRNA-seq· 1Approach:statistical model· 1

Frequent Co-Authors

Aitziber LópeziD· 1 sharedAnna MondinoiD· 1 sharedAraceli Aguilar-GonzáleziD· 1 sharedArianna PocaterraiD· 1 sharedAscensión López-Dı́az de CerioiD· 1 sharedConcepción MarañóniD· 1 sharedConcha HerreraiD· 1 sharedDerya Bakırdöğen· 1 shared

Activity by Year

2022-2026 · peak 1/yr
012022: 1 paper (click to filter)120222023: 0 papers20232024: 0 papers20242025: 0 papers20252026: 1 paper (click to filter)12026

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links
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Justicia-LirioAitziber López · 1 shared paperLópez · 1Anna Mondino · 1 shared paperMondino · 1Arianna Pocaterra · 1 shared paperPocaterra · 1Ascensión López-Dı́az de Cerio · 1 shared paperCerio · 1Derya Bakırdöğen · 1 shared paperBakırdöğen · 1Diego Alignani · 1 shared paperAlignani · 1Felipe Prósper · 1 shared paperPrósper · 1Araceli Aguilar-González · 1 shared paperAguilar-Gonz… · 1Concepción Marañón · 1 shared paperMarañón · 1Concha Herrera · 1 shared paperHerrera · 1
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1 shared paperGenomics
Aitziber LópezORCID

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2 papers

Recent·Most cited

Rapid and dynamic reprogramming within the tumor microenvironment drives EDA-CAR-T dysfunction and compromised therapeutic efficacy in solid tumors

Rodrigo A Redondo-Frutos, Pedro Justicia-Lirio, María Eréndira Calleja-Cervantes, Patxi San Martín‐Úriz, Paula Aguirre-Ruiz, Lorea Jordana-Urriza, Maider Garnica-Suberviola, Sergio Camara-Peña, Diego Alignani, Aitziber López, Saray Rodríguez-Diaz, Rebeca Martínez-Turrillas, Marta Gorraiz, Derya Bakırdöğen, Arianna Pocaterra, , Juan R. Rodríguez-Madoz

This study uses single-cell RNA sequencing to analyze EDA-CAR-T cell dynamics in the tumor microenvironment, revealing temporal reprogramming toward dysfunction and identifying immunosuppressive pathways that impair therapeutic efficacy in solid tumors.

bioRxiv · May 3, 2026 · PreprintGenomics