Grant S. Hansman

This paper introduces MAGE, a model that generates paired human antibody sequences against specific targets, validated against SARS-CoV-2, H5N1, and RSV-A.

This paper identifies and analyzes two types of neutralizing Nanobodies against murine norovirus, revealing structural vulnerabilities in the capsid that could inform antiviral development.

The paper determines the cryo-EM structure of GII.4 norovirus VLPs and finds they exhibit T=4 symmetry, with structural and antigenic differences compared to T=3 VLPs.

This paper shows that a monoclonal antibody (10E9) blocks norovirus by competing with HBGA binding and neutralizes virus in cell culture, despite antigenic drift in GII.4 variants.