Alexis K. Janke

The paper identifies a human antibody that neutralizes RSV and hMPV by targeting a novel epitope spanning multiple antigenic sites, showing cross-protection in a mouse model.

This paper develops computational methods to predict epitope overlaps in antibodies, showing improved accuracy using contrastive learning and demonstrating their utility in antibody discovery.

The paper isolates glycan-reactive antibodies from HIV-1 vaccine trial participants and finds they neutralize diverse HIV strains and show broad cross-reactivity against other pathogens.

This paper introduces MAGE, a model that generates paired human antibody sequences against specific targets, validated against SARS-CoV-2, H5N1, and RSV-A.

This paper designs antigen-specific antibody CDRH3 sequences using AI and germline-based templates, validated against SARS-CoV-2.