The Rab GEF VINE couples phosphatase recruitment to GAP-mediated Rab5 inactivation
Mia S. Frier, Shawn P. Shortill, Michael Davey, Elizabeth Conibear
The paper identifies VINE, a VPS9-family GEF complex, as a regulator of Rab5 inactivation through phosphatase recruitment and GAP-mediated dephosphorylation.