Author

Mia S. Frier

University of British ColumbiaORCID 0000-0002-5634-3235Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:yeast· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

Elizabeth ConibeariD· 2 shared Michael DaveyiD· 2 shared Shawn P. ShortilliD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

3 top collaborators · 3 mutual co-author links

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2 shared papersCell Biology

Elizabeth ConibearORCID

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2 papers

Recent·Most cited

Cell BiologyMolecular Biology of the CellPeer-reviewedSep 9, 2026

The VPS9-family GEF VINE activates Ypt10 in a late endosomal Rab cascade

Mia S. Frier, Michael Davey, Elizabeth Conibear

This paper identifies VINE as a dual Rab regulator that activates Ypt10 and suppresses Vps21 to control late endosomal Rab signaling in yeast.

DOI 10.1091/mbc.e26-07-0303

yeastexperimental assay

𝕏 PostBluesky

Cell BiologyThe Journal of Cell BiologyPeer-reviewedJul 7, 2026

The Rab GEF VINE couples phosphatase recruitment to GAP-mediated Rab5 inactivation

Mia S. Frier, Shawn P. Shortill, Michael Davey, Elizabeth Conibear

The paper identifies VINE, a VPS9-family GEF complex, as a regulator of Rab5 inactivation through phosphatase recruitment and GAP-mediated dephosphorylation.

1 citation

yeastexperimental assay

𝕏 PostBluesky