Ruzanna Shkhyan

This study shows that inhibiting a non-canonical gp130 signaling pathway reduces chronic inflammation and multimorbidity in a high-fat diet model.

This study examines DNA methylation changes in human chondrocytes across ontogeny and develops an epigenetic clock showing STAT3 agonist reduces epigenetic age in aged chondrocytes.

This study identifies a gp130 signaling module that enhances tissue regeneration and prevents pathological outcomes by modulating cellular stress responses.