Author

Iden A. Sapse

Icahn School of Medicine at Mount SinaiORCID 0000-0001-8788-7107Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Immunology· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Assay:CITE-seq· 1 Research Focus:differential expression· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Florian KrammeriD· 3 shared Goran BajiciD· 3 shared Viviana R. SimoniD· 3 shared Ali H. EllebedyiD· 2 shared Daniel C. AdelsbergiD· 2 shared Gagandeep SinghiD· 2 shared Ariel J. RaskiniD· 1 shared Bailey Bozarth· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersImmunology

Florian KrammerORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

ImmunologybioRxivPreprintMar 4, 2026

Defining the Antigenic Topology and Prospective Binding Breadth of Vaccination-induced SARS-CoV-2 Neutralizing Antibodies

Deepika Jaiswal, Clara G. Altomare, Daniel C. Adelsberg…·Goran Bajic

The paper characterizes early vaccine-induced antibodies against SARS-CoV-2, showing some are broad and potent while others are more variant-sensitive.

DOI 10.64898/2026.03.03.709398

humanstructural biology

𝕏 PostBluesky

ImmunologybioRxivPreprintMar 7, 2025

Convergent and clonotype-enriched mutations in the light chain drive affinity maturation of a public antibody

Vishal Rao, Iden A. Sapse, Hallie Cohn…·Camila H. Coelho

The paper identifies clonotype-enriched mutations in the light chain of a public antibody that enhance affinity for a conserved viral epitope and increase after repeated vaccinations.

3 citations

humanCITE-seq

𝕏 PostBluesky

ImmunologyCell ReportsPeer-reviewedNov 1, 2024

Protective effect and molecular mechanisms of human non-neutralizing cross-reactive spike antibodies elicited by SARS-CoV-2 mRNA vaccination

Jordan J. Clark, Irene Hoxie, Daniel C. Adelsberg…·Florian Krammer

This study identifies non-neutralizing antibodies from vaccinated individuals that protect against SARS-CoV-2 in animal models, highlighting their role through Fc-mediated effector functions and conserved epitope binding.

43 citationstop 1%

humanproteomics

𝕏 PostBluesky