Ali H. Ellebedy

This study designs miniprotein inhibitors targeting bacterial adhesins to prevent and treat urinary tract infections.

An mRNA-based influenza vaccine induces broader and more durable B cell responses compared to inactivated influenza virus vaccine in humans.

The paper assesses the breadth and vulnerability of vaccine-induced SARS-CoV-2 neutralizing antibodies against emerging variants by analyzing their binding to conserved and variant-associated epitopes.

Booster SARS-CoV-2 mRNA vaccine recruits and broadens GC B cell responses targeting a highly conserved site on receptor binding domain of spike glycoprotein.

This study identifies two monoclonal antibodies against FimH adhesin that protect mice from E. coli UTI by sterically blocking FimH function, offering an antibiotic-sparing treatment strategy.

The paper examines the receptor-binding specificity of a bovine HPAI H5N1 virus using multiple assays and finds it preferentially binds avian-type receptors.

This study identifies non-neutralizing antibodies from vaccinated individuals that protect against SARS-CoV-2 in animal models, highlighting their role through Fc-mediated effector functions and conserved epitope binding.

This study identifies key structural and glycosylation features of EtpA, an ETEC adhesin, and shows how antibodies target different epitopes to influence immune responses and pathogen-host interactions.