Clonotype specificity distinguishes epitope-tailored and permissive somatic hypermutation
Vishal N. Rao, Bruno Bonnettaz, Alesandro Civljak…·Goran Bajic
The paper shows that clonotype-restricted somatic hypermutations (SHMs) are associated with cryptic epitope recognition, while shared SHMs are permissive and not specific to particular epitopes.