Kilian Schnelle

This study reports cryo-EM structures of human ABCA2, revealing its cholesterol transport mechanism and novel conformational changes.

The paper uses cryo-EM to study P-glycoprotein in different environments, revealing distinct roles of transmembrane helices 4 and 10 in its functional plasticity.

This study systematically analyzes the conformational spectrum of the bacterial ABC transporter MsbA in twelve different membrane mimetics using cryo-EM, revealing environment-specific structural responses.

The paper presents the cryo-EM structure of the human histamine H2 receptor complexed with Gs protein in lipid nanodiscs, revealing insights into ligand binding and G protein coupling mechanisms.