Molecular BiologybioRxivPreprint
Cryo-EM structure of cell-free synthesized human histamine H2 receptor coupled to heterotrimeric Gs protein in lipid nanodisc environment
Zoe Köck, Kilian Schnelle, Margherita Persechino…·Frank Bernhard
The paper presents the cryo-EM structure of the human histamine H2 receptor complexed with Gs protein in lipid nanodiscs, revealing insights into ligand binding and G protein coupling mechanisms.
DOI 10.1101/2023.07.27.550782