Cell BiologybioRxivPreprint
Determination of the cellular target engagement by direct-to-biology Cellular Thermal Shift Assay (CETSA)
Magdalena M. Szewczyk, Darshil Patel, Sarvatit Patel…·Vijayaratnam Santhakumar
This paper demonstrates a direct-to-biology CETSA approach to evaluate cellular target engagement without purification, showing unpurified compounds can be used for assessment.
DOI 10.64898/2026.02.28.708721