Carla Distasi

The paper shows that an optimal ER-mitochondria distance of ~20 nm is critical for efficient Ca2+ transfer and mitochondrial oxidative metabolism, with reduced distances observed in Parkinson's disease astrocytes.

This study shows that deleting calcineurin in astrocytes leads to proteome changes resembling Alzheimer's and epilepsy, and increases seizure risk in mice.

This study shows that deleting calcineurin in astrocytes impairs neuronal excitability in the cerebellum and hippocampus by reducing Na+/K+-ATPase activity.