Aistė Jekabsone

This study examines how psoriasis-like inflammation affects mitochondrial structure and function in keratinocytes and fibroblasts, revealing cell-specific changes.

The paper shows that an optimal ER-mitochondria distance of ~20 nm is critical for efficient Ca2+ transfer and mitochondrial oxidative metabolism, with reduced distances observed in Parkinson's disease astrocytes.

The paper examines how SARS-CoV-2 spike protein RBD affects mitochondrial function and inflammation in three human cell types, finding increased mitoROS and cytokine expression in all, with HLMVEC showing the strongest response.