Lucía Díaz

This study investigates the mechanism of ClC-5 antiporter function and how a specific deletion causes Dent's disease, showing how simulations can aid in understanding rare diseases and personalized medicine.

This study combines AI/physics-based computation and phage display to design high-affinity Affilin(R) proteins targeting HER3, achieving successful theranostic candidates with high affinity and stability.

The paper uses Monte Carlo simulations to analyze the dynamic energy landscapes of PROTAC ternary complexes, identifying stable conformations and supporting PROTAC optimization.

This study identifies novel SETD8 inhibitors and shows their toxicity correlates with ribosome biogenesis regulators, suggesting a biomarker for targeted cancer therapy.