Author

Matúš Medo

University of BernORCID 0000-0001-8865-9085Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:simulation· 1

Frequent Co-Authors

Adrian F. OchsenbeiniD· 1 shared Adrienne VancuraiD· 1 shared Ai Ming Tham· 1 shared Álvaro AndradesiD· 1 shared Andrés LanzósiD· 1 shared Ante Mihaljevic· 1 shared Archa H. FoxiD· 1 shared Bernard Mefi Merlin· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenomics

Adrian F. OchsenbeinORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintOct 25, 2023

Replicability of bulk RNA-Seq differential expression and enrichment analysis results in cancer research

Peter Methys Degen, Matúš Medo

This study evaluates the replicability of RNA-Seq differential expression and enrichment analysis in cancer research, finding that underpowered experiments produce inflated effect sizes and limited replicability.

DOI 10.1101/2023.10.25.563901

bulk RNA-seqsimulation

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GenomicsNature CommunicationsPeer-reviewedJun 8, 2023

Tumour mutations in long noncoding RNAs enhance cell fitness

Roberta Esposito, Andrés Lanzós, Tina Uroda…·Rory Johnson

The paper identifies mutated long noncoding RNAs (lncRNAs) as contributors to tumour cell fitness through experimental validation of their oncogenic effects.

22 citations

humanwhole-exome sequencing

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