Author

Valerie F. Boltz

National Cancer InstituteORCID 0000-0001-8872-5599Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:whole-genome sequencing· 2 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

John M. CoffiniD· 2 shared Mary F. KearneyiD· 2 shared Wei ShaoiD· 2 shared Adam A. CapoferriiD· 1 shared Carlo SacdalaniD· 1 shared Clarissa Halpern· 1 shared Frank M. MaldarelliiD· 1 shared Jason W. RauschiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersMicrobiology

John M. CoffinORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintAug 26, 2026

Ultrasensitive single-genome sequencing reveals strong purifying selection in acute HIV-1 infection

Adam A. Capoferri, Valerie F. Boltz, Wei Shao…·Mary F. Kearney

This study uses ultra-deep single-genome sequencing to show strong purifying selection in early HIV-1 infection, with limited early genetic divergence from founder viruses.

DOI 10.64898/2026.08.21.746200

humanwhole-genome sequencing

𝕏 PostBluesky

BioinformaticsbioRxivPreprintDec 6, 2019

HIV-DRLink: A tool for detecting linked HIV-1 drug resistance mutations in next generation sequencing data

Wei Shao, Valerie F. Boltz, Junko Hattori…·Mary F. Kearney

HIV-DRLink detects linked HIV-1 drug resistance mutations in next-generation sequencing data to predict treatment failure.

DOI 10.1101/866715

humanwhole-genome sequencing

𝕏 PostBluesky