NeuroscienceProceedings of the National Academy of SciencesPeer-reviewed
Altered integration of excitatory inputs onto the basal dendrites of layer 5 pyramidal neurons in a mouse model of Fragile X Syndrome
Diana E. Mitchell, Soledad Miranda‐Rottmann, Maxime G. Blanchard, Roberto Araya
This study investigates synaptic integration in a mouse model of Fragile X Syndrome and finds sublinear summation of excitatory inputs in layer 5 pyramidal neurons, suggesting altered sensory and predictive input processing in ASD.