Author

Soledad Miranda‐Rottmann

CHU Sainte-Justine Research CenterORCID 0000-0001-8384-8661Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1 Assay:imaging· 1 Approach:statistical model· 1

Frequent Co-Authors

Roberto ArayaiD· 4 shared Diana E. MitchelliD· 3 shared Maxime G. BlanchardiD· 2 shared Sabrina Tazerart· 2 shared Anand SureshiD· 1 shared Anis ContractoriD· 1 shared Anne TraniD· 1 shared Bruno Navea Pina· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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4 shared papersNeuroscience

Roberto ArayaORCID

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4 papers

Recent·Most cited

NeuroscienceNeuronPeer-reviewedMay 18, 2026

Translatome profiling reveals opposing alterations in inhibitory and excitatory neurons of Fragile X mice and identifies EPAC2 as a therapeutic target.

Anand Suresh, Nazim Kourdougli, Toshihiro Nomura…·Carlos Portera‐Cailliau

3 citationstop 2%

mousebulk RNA-seq

𝕏 PostBluesky

NeuroscienceProceedings of the National Academy of SciencesPeer-reviewedJan 3, 2023

Altered integration of excitatory inputs onto the basal dendrites of layer 5 pyramidal neurons in a mouse model of Fragile X Syndrome

Diana E. Mitchell, Soledad Miranda‐Rottmann, Maxime G. Blanchard, Roberto Araya

This study investigates synaptic integration in a mouse model of Fragile X Syndrome and finds sublinear summation of excitatory inputs in layer 5 pyramidal neurons, suggesting altered sensory and predictive input processing in ASD.

17 citations

𝕏 PostBluesky

NeuroscienceThe Journal of PhysiologyPeer-reviewedFeb 22, 2022

Selective activation of BK channels in small-headed dendritic spines suppresses excitatory postsynaptic potentials

Sabrina Tazerart, Maxime G. Blanchard, Soledad Miranda‐Rottmann…·Roberto Araya

The paper shows that BK channels in small-headed dendritic spines reduce EPSP amplitude and enhance calcium signals, suggesting a role in synaptic regulation.

22 citations

electronic health recordsexperimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintJun 6, 2019

A spike-timing-dependent plasticity rule for single, clustered and distributed dendritic spines

Sabrina Tazerart, Diana E. Mitchell, Soledad Miranda‐Rottmann, Roberto Araya

The paper investigates spike-timing-dependent plasticity (STDP) in dendritic spines, showing that clustered spines enhance LTP while suppressing LTD.

3 citations

experimental assay

𝕏 PostBluesky