Author

Keiko Sakamoto

National Institutes of HealthORCID 0000-0001-8957-3232Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Akriti GuptaiD· 1 shared Amy Zhang· 1 shared Anthony J. St. LegeriD· 1 shared Benjamin H. SchwarziD· 1 shared Biying XuiD· 1 shared Crystal L. RichardsiD· 1 shared Eric BohrnseniD· 1 shared Guillaume GaudiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Akriti GuptaORCID

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1 paper

Recent·Most cited

Commensal-derived Trehalose Monocorynomycolate Triggers γδ T Cell-driven Protective Ocular Barrier Immunity

Xiaoyan Xu, Yannis Rigas, Mary Joseph Mattapallil, Jing Guo, Keiko Sakamoto, Keisuke Nagao, Vijayaraj Nagarajan, Eric Bohrnsen, Crystal L. Richards, Akriti Gupta, Guillaume Gaud, Paul E. Love, Timothy Jiang, Amy Zhang, Biying Xu, , Rachel R Caspi

This paper identifies trehalose monocorynomycolate (TMCM) from C. mast as a stimulator of IL-17-producing γδ T cells at the ocular surface, which protects against corneal infection.

Immunity · Jan 19, 2026Peer-reviewedImmunology