Nanobody MET CAR T cells show efficacy in solid tumors
Po‐Han Chen, Qin Li, Sam Deveraux…·Samuel G. Katz
This study demonstrates that MET-targeting VHH-CAR-T cells effectively kill tumor cells in vitro and control tumor growth in vivo.
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Yale UniversityORCID 0000-0001-8959-5263Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
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Po‐Han Chen, Qin Li, Sam Deveraux…·Samuel G. Katz
This study demonstrates that MET-targeting VHH-CAR-T cells effectively kill tumor cells in vitro and control tumor growth in vivo.
Jun-Ping Bai, Micheal C. Stankewich, Jie Yang…·Dhasakumar S. Navaratnam
This study shows that knocking out alpha2 spectrin in postnatal outer hair cells leads to a dissociation of prestin's gating charge movement from electromotility and structural changes in the SSC and plasma membrane-SSC space.
Michael C. Stankewich, Jun-Ping Bai, Paul R. Stabach…·Dhasakumar S. Navaratnam
This study shows that βV spectrin knockout mice have normal outer hair cell function but reduced auditory brainstem response amplitudes and fewer nerve fibers, indicating βV spectrin's role in neuronal structure rather than OHC function.