Samuel G. Katz

This study shows that inhibiting DNMT1 improves CD8+ T cell function in the tumor microenvironment and enhances the effectiveness of immune checkpoint inhibitors in a melanoma model.

This study demonstrates that MET-targeting VHH-CAR-T cells effectively kill tumor cells in vitro and control tumor growth in vivo.

This paper introduces RAEFISH, a spatial transcriptomics technology that achieves whole-genome coverage and single-molecule resolution in intact tissues, enabling comprehensive analysis of RNA localization and cell interactions.

The paper shows that non-coding alternative transcripts enable translation of iORFs, and that iORF-encoded proteins have distinct functions from their overlapping annotated proteins.