Sjoerd J. van Deventer

Metabolic regulation of cytokine responses in diffuse large B-cell lymphoma

This study investigates how metabolic pathways influence cytokine production in diffuse large B-cell lymphoma, finding that glycolysis modulation affects IL-6, IL-10, and TNFα levels and that DLBCL subtypes respond differently to IL-4.

DuoHexaBody-CD37 induces direct cytotoxic signaling in diffuse large B-cell lymphoma

This study shows that DuoHexaBody-CD37 induces direct cytotoxicity in DLBCL cells through CD37 clustering and signaling changes, independent of subtype.

Tetraspanin CD82 reduces the formation of CADM1 oligomers

This study shows CD82 reduces CADM1 oligomer formation by interacting with its extracellular domains, affecting transmembrane helix spacing and disrupting cell adhesion.