Author

Isaac Darko Otchere

University of GhanaORCID 0000-0001-8982-9488Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:statistical model· 4 Assay:whole-genome sequencing· 3 Organism:bacteria (other)· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:variant calling· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Martín AntonioiD· 4 shared Bouke Catherine de JongiD· 3 shared Conor Joseph MeehaniD· 3 shared Dorothy Yeboah‐ManuiD· 3 shared Julian ParkhilliD· 3 shared Mireia CoscolláiD· 3 shared N'Dira SanoussiiD· 3 shared Sébastien GagneuxiD· 3 shared

Activity by Year

2018-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersGenomics

Martín AntonioORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Upper respiratory tract bacterial microbiome features associated with Streptococcus pneumoniae colonisation, environmental and demographic factors among older children in a rural setting in The Gambia

Dam Khan, Brenda Kwambana-Adams, Peggy Estelle Tientcheu, Shola Able-Thomas, Josh L. Espinoza, Gavin John, Tiana Mamaghani, Peter Sylvanus Ndow, Ma-Ansu Kinteh, Archibald Kwame Worwui, Isaac Darko Otchere, Nuredin Ibrahim Mohammed, Mark Patrick Nicol, Christopher L. Dupont, Martín Antonio

The study examines URT microbiome features linked to S. pneumoniae colonisation in older children in The Gambia, identifying microbial associations and environmental factors influencing colonisation.

bioRxiv · Oct 5, 2026 · PreprintMicrobiology

Potential benefits of Soymilk-burkina (Agbenu) consumption on gut health of women of reproductive age

Isaac Darko Otchere, Emmanuel Kyereh, Ethel Juliet Serwa Blessie, Isaac Agbemafle, Kwasi Agyenkwa-Mawuli, Kwabena Dentu Gyampo, Akua A. Afrane Arthur, C. B. Galley, Getrude Bubune Ahegbebu, Frank Peget, Nelson Kobla Amey, Richard L.K. Glover, Mary Glover‐Amengor

This study examines the impact of soymilk-burkina and soymilk-millet blend on gut microbiome composition in women of reproductive age, finding transient beneficial effects on specific bacterial taxa.

Nutrition and Dietary Supplements · Dec 1, 2025Peer-reviewedMicrobiology

Mycobacterium tuberculosis complex lineage 5 exhibits high levels of within-lineage genomic diversity and differing gene content compared to the type strain H37Rv

N'Dira Sanoussi, Mireia Coscollá, Boatema Ofori-Anyinam, Isaac Darko Otchere, Martín Antonio, Stefan Niemann, Julian Parkhill, Simon R. Harris, Dorothy Yeboah‐Manu, Sébastien Gagneux, Leen Rigouts, Dissou Affolabi, Bouke Catherine de Jong, Conor Joseph Meehan

The paper identifies high within-lineage genomic diversity and gene content differences in Mycobacterium tuberculosis complex lineage 5 compared to H37Rv, affecting transmission analysis and suggesting the need for alternative reference genomes.

Microbial Genomics · Jul 9, 2021Peer-reviewedGenetics

Phylogenomics of Mycobacterium africanum reveals a new lineage and a complex evolutionary history

Mireia Coscollá, Sébastien Gagneux, Fabrizio Menardo, Chloé Loiseau, Paula Ruiz-Rodríguez, Sònia Borrell, Isaac Darko Otchere, Adwoa Asante-Poku, Prince Philip Ankapong Asare, Leonor Sánchez-Busó, Florian Gehre, N'Dira Sanoussi, Martín Antonio, Dissou Affolabi, Janet Fyfe, , Daniela Brites

The paper analyzes genomes of Mycobacterium africanum strains to identify a new lineage and explore their evolutionary history and phylogeography.

Microbial Genomics · Feb 1, 2021Peer-reviewedGenomics

Comparative genomics of Mycobacterium africanum Lineage 5 and Lineage 6 from Ghana suggests different ecological niches

Isaac Darko Otchere, Mireia Coscollá, Leonor Sánchez-Busó, Adwoa Asante-Poku, Daniela Brites, Chloé Loiseau, Conor Joseph Meehan, Stephen Osei-Wusu, Audrey G. Forson, Clement Laryea, Abdallah Iddrisu Yahayah, Akosua Baddoo, Gloria Akosua Ansa, Samuel Yaw Aboagye, Prince Philip Ankapong Asare, , Dorothy Yeboah‐Manu

The paper compares the genomes of Mycobacterium africanum Lineage 5 and 6 from Ghana, finding genomic diversity and selection pressure differences suggesting distinct ecological niches.

Scientific Reports · Jul 20, 2018Peer-reviewedGenomics