Harry J. Whitwell

The paper identifies stage-specific synaptic proteomic signatures in Alzheimer's disease and links them to plasma proteins associated with disease progression and cognitive decline.

This study develops an organ-on-chip model to investigate respiratory-vascular interactions under oxidative stress, revealing how airway injury drives vascular inflammation and remodeling in COPD.

The paper identifies a novel gel-like proteasome condensate, TAADs, that facilitates aggregate clearance but may contribute to neurodegenerative disorders if aggregates persist.

This study identifies a synaptic-astrocytic proteomic signature associated with synapse loss in Alzheimer's Disease across different disease stages.

The paper analyzes mitochondrial genome variation across human populations to identify co-mutation patterns and epistatic interactions, finding subpopulation-specific biases in mutation clustering.