Author

John Dozier Gordan

University of California, San FranciscoORCID 0000-0001-8997-5725Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Aidan KeithiD· 1 shared Changliang He· 1 shared Dominique C. MitchelliD· 1 shared Gary K.L. ChaniD· 1 shared Jin Liu· 1 shared Jonathan M. L. OstremiD· 1 shared Kliment A. VerbaiD· 1 shared LeeAnn Wang· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Aidan KeithORCID

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2 papers

Recent·Most cited

BiochemistryCell chemical biologyPeer-reviewedAug 1, 2026

Small molecule activation of the tumor suppressor kinase LKB1

Lin Song, Dominique C. Mitchell, Jin Liu…·John Dozier Gordan

This study develops small molecules that activate the tumor suppressor kinase LKB1 and shows their therapeutic benefits in cancer cell lines.

3 citations

humanexperimental assay

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Cancer BiologybioRxivPreprintJul 24, 2026

A transcriptional signature of LKB1 functional loss defines a large, therapeutically addressable patient population across human cancers

Sourav Bandyopadhyay, John Dozier Gordan

The paper identifies a 30-gene transcriptional signature that detects LKB1 functional loss in tumors, revealing a larger patient population than genomic loss alone.

DOI 10.64898/2026.07.23.740219

humanbulk RNA-seq

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