Systems BiologybioRxivPreprint
Insulin Signaling-independent Activation of DAF-16 Shapes the Transcriptome during Normal Aging
Shang‐Tong Li, Hanqing Zhao, Pan Zhang…·Meng‐Qiu Dong
This study shows that DAF-16, a transcription factor, activates gene expression during aging in C. elegans independently of insulin signaling, stabilizing the transcriptome against age-related stress.
DOI 10.1101/284083