Chung‐Yi Liang

This study presents a single-nucleus transcriptomic atlas of Drosophila treated with rapamycin, identifying a sex-biased convergent aging trajectory and its modulation by rapamycin.

This study identifies Tet as a critical regulator of intestinal stem cell establishment and homeostasis through single-nucleus transcriptomic analysis.

The paper uses snRNA-seq in Drosophila to study how AD-associated proteins affect peripheral tissues, finding distinct impacts of Aβ42 and Tau on sensory neurons and non-neuronal tissues.

The paper presents an aging Drosophila cell atlas, identifies cell type-specific aging patterns, and shows ribosomal gene expression as a conserved aging predictor.

This study shows that DAF-16, a transcription factor, activates gene expression during aging in C. elegans independently of insulin signaling, stabilizing the transcriptome against age-related stress.