Author

Pornpimol Charoentong

Innsbruck Medical UniversityORCID 0000-0001-9028-725XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:deconvolution· 2 Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:clinical cohort / trial· 1

Frequent Co-Authors

Dietmar RiederiD· 3 shared Francesca FinotelloiD· 3 shared Hubert HackliD· 3 shared Zlatko TrajanoskiiD· 3 shared Anne KrogsdamiD· 2 shared Clemens Mayer· 2 shared Mirjana EfremovaiD· 2 shared Christina PlattneriD· 1 shared

Activity by Year

2017-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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3 shared papersGenomics

Dietmar RiederORCID

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3 papers

Recent·Most cited

BioinformaticsGenome MedicinePeer-reviewedMay 24, 2019

✦ In-depth digest

Molecular and pharmacological modulators of the tumor immune contexture revealed by deconvolution of RNA-seq data

Francesca Finotello, Clemens Mayer, Christina Plattner…·Zlatko Trajanoski

quanTIseq estimates absolute fractions of ten immune cell types from bulk RNA-seq; across TCGA, CXCL9/CXCR3 expression, not mutational load, tracks CD8+ T cell infiltration.

1,546 citationstop 1%

humanbulk RNA-seq

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GenomicsNature CommunicationsPeer-reviewedDec 27, 2017

Targeting the PD-1/PD-L1 pathway potentiates immunoediting and changes the dynamics of neutral evolution in a mouse model of colorectal cancer

Mirjana Efremova, Dietmar Rieder, Victoria Klepsch…·Zlatko Trajanoski

This study shows that neutral evolution dominates tumor shaping in a mouse CRC model, and PD-1/PD-L1 blockade enhances immunoediting and tumor homogeneity.

299 citationstop 2%

mousestatistical model

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GenomicsCell ReportsPeer-reviewedJan 1, 2017

✦ In-depth digest

Pan-cancer immunogenomic analyses reveal genotype-immunophenotype relationships and predictors of response to checkpoint blockade

Pornpimol Charoentong, Francesca Finotello, Mihaela Angelova…·Zlatko Trajanoski

Immunogenomic profiling of 8243 TCGA samples across 20 solid cancers yields an immune atlas and a random-forest-derived immunophenoscore stratifying melanoma responders to checkpoint blockade.

5,042 citationstop 1%

humanbulk RNA-seq

𝕏 PostBluesky