Author

Arthur H.M. Burghes

The Ohio State UniversityORCID 0000-0001-9031-1555Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Jacob A. Slivka· 2 shared Anton J. BlatnikiD· 1 shared Benjamin PastoreiD· 1 shared Caleb M. EmbreeiD· 1 shared Elaina P. Boyle· 1 shared Guramrit SinghiD· 1 shared Manu Sanjeev· 1 shared Michael G. KearseiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMolecular Biology

Jacob A. Slivka

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2 papers

Recent·Most cited

Molecular BiologyNucleic Acids ResearchPeer-reviewedAug 2, 2025

Sm-site containing mRNAs can accept Sm-rings and are downregulated in Spinal Muscular Atrophy

Anton J. Blatnik, Manu Sanjeev, Jacob A. Slivka…·Arthur H.M. Burghes

The paper identifies Sm-site containing mRNAs that can accept Sm-rings and shows their downregulation in Spinal Muscular Atrophy.

DOI 10.1093/nar/gkaf794

𝕏 PostBluesky

Molecular BiologyRNAPeer-reviewedMar 6, 2023

Translation re-initiation after uORFs does not fully protect mRNAs from nonsense-mediated decay

Paul J Russell, Jacob A. Slivka, Elaina P. Boyle…·Michael G. Kearse

The paper investigates how uORF length affects translation re-initiation and mRNA stability, finding that re-initiation does not robustly protect mRNAs from NMD.

30 citations

humanbulk RNA-seq

𝕏 PostBluesky