ImmunologyImmunology and Cell BiologyPeer-reviewed
Transcriptomic signatures of host immune responses in aphthous ulcers, the earliest lesions of Crohn's disease, suggest that a bacterial invasive challenge, rather than global dysbiosis, is the initiating factor.
Phillip J Whiley, Ojas V. A. Dixit, Mukta Das Gupta…·Claire Louise O'Brien
The paper identifies transcriptomic signatures in aphthous ulcers of Crohn's disease, suggesting bacterial invasion initiates inflammation rather than dysbiosis.
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