Riccardo Pecori

Benchmarking Software for DDA-PASEF Immunopeptidomics

This study benchmarks DDA-PASEF immunopeptidomics software tools, showing PEAKS identifies the most immunopeptides, while database size affects performance across platforms.

m6A regulates ADAR1 mediated RNA editing during macrophage activation

This study investigates the interaction between m6A and A-to-I RNA modifications in macrophages, showing that ~60% of genes are m6A-modified and ~12% have A-to-I editing sites, with ~10% overlapping.

MAETi: Mild acid elution in a tip enables immunopeptidome profiling from 1E4 cells

MAETi enables immunopeptidome profiling from 1E4 cells with high peptide coverage and SAV epitope detection.

MultiEditR: An easy validation method for detecting and quantifying RNA editing from Sanger sequencing

MultiEditR is a tool that detects and quantifies RNA editing from Sanger sequencing, offering a cost-effective validation method for RNA editing sites.

Dimerisation of APOBEC1 is dispensable for its RNA/DNA editing activity and modulates its availability

The paper shows that APOBEC1 dimerisation is critical for its activity and availability, and that dimerisation increases DNA damage.

ADAR1 can drive Multiple Myeloma progression by acting both as an RNA editor of specific transcripts and as a DNA mutator of their cognate genes

The paper shows ADAR1 drives Multiple Myeloma progression by editing RNA and causing DNA mutations at editing sites.