Author

Marco Binder

German Cancer Research CenterORCID 0000-0002-5805-6109Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Cell Biology· 1 Microbiology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:fluorescence / live-cell microscopy· 1

Frequent Co-Authors

Ana J. García‐SáeziD· 1 shared Ana Luisa CostaiD· 1 shared Anja Ciprinidis· 1 shared Ann-Kathrin MehnertiD· 1 shared Annette Arnold· 1 shared Annette Schneider· 1 shared Beau R. WebberiD· 1 shared Branden S. MoriarityiD· 1 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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1 shared paperCell Biology

Ana J. García‐SáezORCID

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4 papers

Recent·Most cited

Cell BiologyThe EMBO JournalPeer-reviewedFeb 21, 2025

Spatio-temporal analysis of the innate immune response to cytoplasmic dsDNA using a novel cGAMP biosensor

Steve Smarduch, Sergio David Moreno-Velásquez, Doroteja Ilic…·Sergio P. Acebrón

The paper develops a fluorescent cGAMP biosensor to monitor cGAS-STING signaling dynamics in real-time and across different cellular contexts.

18 citationstop 3%

humanfluorescence / live-cell microscopy

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MicrobiologybioRxivPreprintFeb 3, 2025

The hepatitis E virus capsid protein ORF2 counteracts cell-intrinsic antiviral responses to enable persistence in hepatocytes

Ann-Kathrin Mehnert, Sebastian Stegmaier, Carlos Darío Ramírez…·Viet Loan Dao Thi

This study identifies ORF2 as a key HEV protein that suppresses antiviral responses in hepatocytes, enabling viral persistence.

2 citations

humanbulk RNA-seq

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BioinformaticsMolecular Therapy — Nucleic AcidsPeer-reviewedJul 21, 2021

MultiEditR: An easy validation method for detecting and quantifying RNA editing from Sanger sequencing

Mitchell G. Kluesner, Rafail Nikolaos Tasakis, Taga Lerner…·Riccardo Pecori

MultiEditR is a tool that detects and quantifies RNA editing from Sanger sequencing, offering a cost-effective validation method for RNA editing sites.

36 citations

bulk RNA-seqexperimental assay

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Systems BiologyPLoS PathogensPeer-reviewedOct 1, 2020

Identification of Interleukin1β as an Amplifier of Interferon alpha-induced Antiviral Responses

Katharina Robichon, Tim Maiwald, Marcel Schilling…·Ursula Klingmüller

This study identifies IL1β as an amplifier of IFN-induced antiviral responses through mathematical modeling and experimental validation.

9 citations

mousestatistical model

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