Author

Nicholas W. Chavkin

University of VirginiaORCID 0000-0001-9058-0245Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Organism:human· 1

Frequent Co-Authors

Karen K. HirschiiD· 3 shared Bipul R. AcharyaiD· 2 shared Gaël GenetiD· 2 shared Hema H. VasavadaiD· 2 shared Mahalia HubaiD· 2 shared Nafiisha GenetiD· 2 shared Stephanie P. McDonnelliD· 2 shared Anne EichmanniD· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersMolecular Biology

Karen K. HirschiORCID

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3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintJun 23, 2023

Loss of endothelial cell heterogeneity in arteries after obesogenic diet

Luke S. Dunaway, Melissa A. Luse, Shruthi Nyshadham…·Brant E. Isakson

The paper investigates how an obesogenic diet affects endothelial cell heterogeneity in arteries, finding convergence in transcriptional profiles between mesenteric and adipose arterial endothelial cells in obesity.

DOI 10.1101/2023.06.23.546320

mousehuman

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NeuroscienceCell ReportsPeer-reviewedApr 1, 2023

Connexin 43-mediated Neurovascular Interactions Regulate Neurogenesis in the Adult Brain Subventricular Zone

Nafiisha Genet, Gaël Genet, Nicholas W. Chavkin…·Karen K. Hirschi

This study shows that Cx43-mediated interactions between neural stem cells and endothelial cells in the SVZ regulate NSC quiescence and neurogenesis.

25 citations

mousebulk RNA-seq

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Developmental BiologyNature CommunicationsPeer-reviewedOct 6, 2022

Endothelial Cell Cycle State Determines Propensity for Arterial-Venous Fate

Nicholas W. Chavkin, Gaël Genet, Mathilde Poulet…·Karen K. Hirschi

This study shows that endothelial cell cycle states determine arterial-venous fate, with early G1 for venous and late G1 for arterial specification.

83 citationstop 2%

mousebulk RNA-seq

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