Ambrose Oruni

This study uses genomic data to analyze evolutionary dynamics of Anopheles gambiae under different insecticidal tools, revealing distinct resistance mechanisms and allele frequency shifts.

In Tororo, Uganda, An. funestus tolerated clothianidin-sprayed walls better than An. gambiae yet was killed on pirimiphos-methyl walls up to 7 months post-spray, implicating it in the malaria resurgence.

This paper uses genomic surveillance in a cluster randomized trial to detect insecticide resistance variants in Ugandan Anopheles funestus and An. gambiae s.l., showing differential population responses to pyrethroid and PBO interventions.

RNA-Seq-Pop is a Snakemake workflow for RNA-Seq analysis that identifies pyrethroid resistance mechanisms in Anopheles gambiae by analyzing genetic diversity and differential expression.