Emmanuel Arinaitwe

Circulating T-follicular helper and type I regulatory T cells have overlapping phenotypes in P. falciparum malaria and are maintained by parasite exposure.

The paper characterizes malaria-specific Tfh and Tr1 cells in a longitudinal cohort, finding overlapping phenotypes and showing their decline after transmission interruption.

CXCR6⁺ CD127- Tr1 Cells Balance Immunity and Persistence in Plasmodium falciparum Infection

The paper identifies CXCR6⁺ CD127⁻ Tr1 cells as key regulators in Plasmodium falciparum infection, showing they balance immunity and parasite persistence.

Pfs230 Domain 12 is a potent malaria transmission-blocking vaccine candidate

This study identifies Pfs230 Domain 12 as a potent malaria transmission-blocking vaccine candidate that induces antibodies reducing parasite transmission to mosquitoes.

Inhibitory NK receptors regulate the γδ T cell response to malaria

The paper examines inhibitory NK receptors on γδ T cells in Ugandan children, finding that some enhance and others reduce antimalarial responses to repeated infections.

Significant variations in tolerance to clothianidin and pirimiphos-methyl in Anopheles gambiae and Anopheles funestus populations during a dramatic malaria resurgence despite sustained indoor residual spraying in Uganda

In Tororo, Uganda, An. funestus tolerated clothianidin-sprayed walls better than An. gambiae yet was killed on pirimiphos-methyl walls up to 7 months post-spray, implicating it in the malaria resurgence.